The six sections of this book provide a structure for introducing the concept of special populations for health care, research and policy and the social determinants of those in need of increased attention due to their experiences of adversity, trauma, and other barriers to health. In this book public health is not only a set of programs and services but a way of thinking about health challenges and ways of working to address broad social determinants. This book is cross discipline and cross perspective both required to understand programming and practices in the virtuous health-economy cycle. Intergenerational trauma, undocumented migration and other challenges are discussed through resilience, healing, health professional education, health equity, and models of primary care. Social relationships, choice and cultural continuity are fundamental to individual trajectories for health and can be traced through this work. Critical thinking questions, case studies, recommended readings, related websites and references accompany the chapters and include a biography and glossary.